What is high alkaline phosphatase in toddlers?

What is high alkaline phosphatase in toddlers?

Transient hyperphosphatasemia (TH) of infancy and early childhood is characterized by a marked elevation of serum alkaline phosphatase in the absence of detectable liver or bone disease, with a return to normal levels within weeks or months. Because the condition is thought to be benign, it is also called benign TH.

Is high alkaline phosphatase in children normal?

Normal Results Normal values may vary slightly from laboratory to laboratory. They also can vary with age and gender. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women. The examples above show the common measurements for results for these tests.

What causes alkaline phosphatase high on babies?

Background: Elevated serum alkaline phosphatase (ALP) in infants with intestinal failure (IF) can be due to parenteral nutrition-associated liver disease (PNALD) or metabolic bone disease (MBD).

Can growth spurts cause high alkaline phosphatase?

Normal Results Adults have lower levels of ALP than children. Bones that are still growing produce higher levels of ALP. During some growth spurts, levels can be as high as 500 IU/L or 835 µKat/L. For this reason, the test is usually not done in children, and abnormal results refer to adults.

What causes high alkaline phosphatase?

This could include a blockage in your bile ducts, gallstones, cirrhosis, liver cancer, and some forms of hepatitis. High levels may also indicate a concern related to the bones such as rickets, Paget’s disease, bone cancer, or an overactive parathyroid gland.

What is a high level alkaline phosphatase?

What do the results mean? High alkaline phosphatase levels may mean there is damage to your liver or that you have a type of bone disorder. Liver damage creates a different type of ALP than bone disorders do.

Why the normal value of child alkaline phosphatase is higher than adults?

For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. The normal range for children is higher than that for adults, especially for infants and teens because their bones are growing rapidly.

What causes high Alk Phos?

High alkaline phosphatase levels in the liver may indicate the following conditions: Cholestasis of pregnancy : This is a common liver disease that can develop late in pregnancy. Cirrhosis of the liver : Cirrhosis is a late-stage liver disease in which healthy liver tissue is replaced with scar tissue and the liver is permanently damaged.

What are the reasons for an elevated alkaline phosphatase?


  • Ovarian
  • Prostate
  • Pharynx
  • Testicular
  • What can cause elevated alkaline phosphatase?

    Possible causes of increased levels of plasma alkaline phosphatase include: hepatobiliary disease including: cholestasis: increased synthesis of hepatocyte ALP and increased secretion of high molecular weight form into plasma; elevations of ALP of up to 10 times normal levels

    Do certain foods raise alkaline phosphatase levels?

    This amazing kale pesto is only 210 calories and anti-oxidant rich! Foods rich in zinc, phosphorus and vitamin B12 help increase alkaline phosphatase levels in your body. All of these nutrients can be found in beef, poultry and seafood. Oils, such as coconut and corn, may also raise your alkaline phosphatase.

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