What does EQD2 mean?

These simplified biologically equivalent doses are called either EQD2, denoting equivalent total doses in 2-Gy fractions [13]. Rectal bleeding is a common late toxicity of pelvic radiation.

What is the difference between EQD2 and bed?

The important difference between BED and EQD2 is that BED reports an effective dose, while EQD2 gives the equivalent dose needed in 2 Gy/fx to achieve that effective dose.

What is intracavitary irradiation?

Listen to pronunciation. (IN-truh-KA-vih-tayr-ee RAY-dee-AY-shun THAYR-uh-pee) A type of internal radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into a body cavity such as the chest cavity or the vagina.

What is EQD2 in radiotherapy?

Calculates biologically effective dose (BED) and equivalent dose (EQD2) for cancer radiotherapy. Pearls/Pitfalls. Why Use. Patients undergoing radiation (to compare different fractionation regimens). Note that BED is the biologically effective dose, not biologically equivalent dose.

What is bone irradiation?

Aims and objectives: Extracorporeal irradiation (ECI) is relatively a rare method used in the management of malignant bone tumors (MBT). It consists of en-bloc removal of the tumor bearing bone segment, removal of the tumor from the bone, irradiation, and re-implantation back in the body.

What is local irradiation?

Radiation therapy is called a local treatment. This means that it only affects the area of the body that is targeted. For example, radiation therapy to the scalp may cause hair loss.

What is the study of radiation called?

Radiobiology (also known as radiation biology, and uncommonly as actinobiology) is a field of clinical and basic medical sciences that involves the study of the action of ionizing radiation on living things, especially health effects of radiation.

What is bed Radiobiology?

• BED is a measure of the true biological dose delivered. by a particular combination of dose per fraction and. total dose to a particular tissue characterized by a. specific α/β ratio. • BED is not Biologically Equivalent Dose.

How is EQD2 calculated?

EQD2 was calculated with the equation EQD2 = D × [(d + α/β)/(2 + α/β)], as derived from the linear-quadratic model; D = total dose, d = dose per fraction, α = linear (first-order dose-dependent) component of cell killing, β = quadratic (second-order dose dependent) component of cell killing, α/β ratio = the dose at …

What does intracavity mean?

(IN-truh-KA-vih-tayr-ee) Within a cavity or space, such as the abdomen, pelvis, or chest.

What is the meaning of irradiation?

Definition of irradiation 1 : exposure to radiation (such as X-rays or alpha particles) 2 : the application of radiation (such as X-rays or gamma rays) for therapeutic purposes or for sterilization (as of food) also : partial or complete sterilization by irradiation 3 : irradiance

What is food irradiation and how does it work?

Food irradiation (the application of ionizing radiation to food) is a technology that improves the safety and extends the shelf life of foods by reducing or eliminating microorganisms and insects. Like pasteurizing milk and canning fruits and vegetables, irradiation can make food safer for the consumer.

What is the meaning of radiation?

1 : exposure to radiation (such as X-rays or alpha particles) 2 : the application of radiation (such as X-rays or gamma rays) for therapeutic purposes or for sterilization (as of food) also : partial or complete sterilization by irradiation.

What is irradiation and is it safe?

Like pasteurizing milk and canning fruits and vegetables, irradiation can make food safer for the consumer. The Food and Drug Administration (FDA) is responsible for regulating the sources of radiation that are used to irradiate food. The FDA approves a source of radiation for use on foods only after it has determined that irradiating