What is Meynert nucleus?
The nucleus basalis of Meynert (nbM) was first described at the end of the 19th century and named after its discoverer, Theodor Meynert. The nbM contains a large population of cholinergic neurons that project their axons to the entire cortical mantle, the olfactory tubercle, and the amygdala.
Where is the nucleus of Meynert?
Anatomical terms of neuroanatomy The nucleus basalis, also known as the nucleus basalis of Meynert or nucleus basalis magnocellularis, is a group of neurons located mainly in the substantia innominata of the basal forebrain.
Where is acetylcholine produced Meynert?
The nucleus basalis of Meynert (NBM) is the major source of cholinergic innervation to the neocortex .
What are cholinergic neurons?
A cholinergic neuron is a nerve cell which mainly uses the neurotransmitter acetylcholine (ACh) to send its messages. Many neurological systems are cholinergic.
What is caudate and putamen?
The putamen is also a large structure that is separated from the caudate nucleus by the anterior limb of the internal capsule. The putamen is connected to the caudate head by bridges of cells that cut across the internal capsule.
Where is acetylcholine made?
Acetylcholine is synthesized from choline and acetyl-coenzyme A (acetyl-CoA) in the cytoplasm of the nerve terminal through the enzyme choline acetyltransferase (ChAT).
Where are cholinergic cells?
Cholinergic neurons are also found in the basal forebrain, which is classically segregated into four main regions: the Medial Septal Nucleus (MSN), the vertical and horizontal limbs of the Diagonal Band of Broca (DB), and the Nucleus Basalis (NB) of Meynert.
Why is the caudate nucleus important?
These deep brain structures together largely control voluntary skeletal movement. The caudate nucleus functions not only in planning the execution of movement, but also in learning, memory, reward, motivation, emotion, and romantic interaction.