Can methimazole cause kidney problems?
Drugs in thyroid and renal diseases Hypothyroidism induced by thionamides (methimazole, carbimazole, and propylthiouracil) can cause kidney failure. Thionamides can affect kidney function by different immunological mechanisms leading to the development of different types of glomerulonephritis (113, 114, 115).
Can thyroid medication cause kidney damage in cats?
Due to the hypertension (high blood pressure) that develops with hyperthyroidism, however, damage to the heart, kidneys and eyes can occur. After diagnosis, the majority of cats can be managed with medical therapy, a medication called methimazole.
Does hyperthyroidism mask kidney disease in cats?
There is a definite link between kidney disease and an overactive thyroid in cats. If your cat already suffers from kidney disease, the increased blood flow to the kidneys can help them to function better. In this way, hyperthyroidism can actually mask kidney disease.
Can hyperthyroidism cause kidney problems?
 Thyroid hormone status affects the functioning renal mass (measured as the kidney to body mass ratio), with hypothyroidism reducing this ratio and hyperthyroidism increasing it.  However, severe hyperthyroidism results in protein breakdown and eventual renal atrophy.
What are the side effects of methimazole in cats?
In cats, the most common side effects of methimazole/carbimazole administration are gastrointestinal (hyporexia to anorexia, vomiting, and diarrhea). Most of the gastrointestinal side effects can be controlled by discontinuation of the medication and supportive care.
What are the signs of end stage renal failure in cats?
Symptoms of end stage kidney failure in cats include dull sunken eyes, inability to walk, body odour, incontinence in bladder or bowels, refusal to eat or drink, seizures, confusion, pacing and restlessness, withdrawing, hiding and running away.
Can thyroid function affect kidneys?
Because thyroid hormone has numerous effects on the kidney, heart, and vascular system, thyroid dysfunction can cause significant changes in renal and cardiovascular functions (1–3). In particular, hypothyroidism is known to be associated with reduced renal plasma flow (RPF) and low glomerular filtration rate (GFR).
How long do side effects of methimazole last in cats?
The most common side effects include vomiting, anorexia, and tiredness, and usually occur within the first three months of treatment. Other, less common side effects such as gastrointestinal effects and mild changes in your pet’s blood cell counts are usually temporary and resolve with time.