What is Epidermolytic ichthyosis?

Epidermolytic ichthyosis (EI) specifically refers to a hereditary skin disorder that is characterized by varying degrees of blistering and subsequent reactive scaling of the skin. The underlying histopathology shows mid-epidermal splitting and hyperkeratosis, together referred to as epidermolytic hyperkeratosis (EHK).

What is erythema Toxicum Neonatorum?

Erythema toxicum neonatorum (ETN) is a benign self-limited eruption occurring primarily in healthy newborns in the early neonatal period. Erythema toxicum neonatorum is characterized by macular erythema, papules, vesicles, and pustules, and it resolves without permanent sequelae. See the image below.

How do you describe ichthyosis?

Ichthyosis vulgaris (ik-thee-O-sis vul-GAY-ris) is an inherited skin disorder in which dead skin cells accumulate in thick, dry scales on your skin’s surface.

Is ichthyosis recessive or dominant?

Ichthyosis vulgaris (1:250—1000) has an autosomal dominant inheritance, meaning an abnormal gene is inherited from a parent.

What is bullous ichthyosiform erythroderma?

Bullous congenital ichthyosiform erythroderma, also known as epidermolytic ichthyosis and bullous ichthyosiform erythroderma (and formerly known as epidermolytic hyperkeratosis), is a rare congenital disorder of keratinocytes presenting with blistering at birth and then with hyperkeratosis later in life.

Is erythroderma genetic?

This condition is inherited in an autosomal recessive pattern , which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

Why is it called Harlequin syndrome?

When the nerve bundles are injured, they are not able to communicate with half of the face and body properly. Therefore, that half of the body is not able to respond to stimuli such as exercise by flushing and producing sweat. This causes the Harlequin sign that is associated with this syndrome.

What are collodions?

Collodions are liquid preparations containing pyroxylin in a mixture of ethyl ether and ethanol. A soft brush is used to apply the preparation to the skin. When the solvent evaporates it leaves a film of pyroxylin on the surface.

How to use collodion as an antiseptic?

Also in the preparation of medicated collodion. Mix the ingredients together in a closed container and shake the mixture until the camphor is dissolved. A protective for cuts and small burns. When applied to the skin, it causes pain but it is an effective antiseptic and also exclude air form open wounds.

How do you prepare collodion?

A soft brush is used to apply the preparation to the skin. When the solvent evaporates it leaves a film of pyroxylin on the surface. Definition: Collodion contains not less than 5% of pyroxylin by weight. Dissolve the pyroxylin in the ether and alcohol in a closed container.

How can you tell if a collodion is good?

If the collodion is good, the film is semi-transparent, of a bluish opal-like appearance. Many of the unpleasant markings in collodion pictures may have their origin in the gutta percha. Occasionally, upon sensitising collodion, I have found it assume a deep sherry colour a few hours after being made.