What causes peripheral ossifying fibroma?

Peripheral ossifying fibroma is a benign swelling of the gum, most commonly seen in teenagers and young adults. It is derived from cells of the periodontal ligament and is usually classified as a reactive hyperplasia but sometimes as a benign neoplasm.

What is peripheral ossifying fibroma?

Peripheral ossifying fibroma (POF) is a non-neoplastic entity, which occurs on the gingiva in response to trauma or irritation. It is a reactive lesion of connective tissue and is not the soft-tissue counterpart of central ossifying fibroma.

What causes non ossifying fibroma?

There is no known cause, genetic link, or risk factor involved in the growth of a non-ossifying fibroma (or even two or three). Multiple non-ossifying fibromas are very rare and are associated with two specific conditions: neurofibromatosis and Jaffe-Campanacci Syndrome.

What is peripheral Ameloblastoma?

Peripheral Ameloblastoma (PA) is a benign odontogenic tumor, arising from the cell rest of Serres, reduced enamel epithelium and basal cells of the surface epithelium. Peripheral ameloblastoma is a rare odontogenic neoplasm occurring commonly in the mandibular gingiva.

What is peripheral giant cell granuloma?

Peripheral giant cell granuloma (PGCG) is the most common oral giant cell lesion appearing as a soft tissue extra-osseous purplish-red nodule consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells.

What is peripheral odontogenic fibroma?

Peripheral odontogenic fibroma (formerly known as fibromatous and ossifying epulis) is a benign, often slow-growing tumor that arises from periodontal structures (gums, ligaments, and bone). They can be further sub-classified as peripheral odontogenic fibromas and acanthomatus ameloblastomas.

What causes cortical defect?

How is a fibrous cortical defect caused? The basic pathology is a fibrous proliferation arising from the periosteum and is probably based upon a developmental defect. The etiology of fibrous cortical defects though still remains unknown.

What is malignant Ameloblastoma?

Malignant ameloblastoma is a rare odontogenic tumor accounting for about 2% of the ameloblastic tumors. 1. The term “malignant ameloblastoma” describes a tumor having benign histological features but showing evidence of metastasis.

What is peripheral ossifying fibroma (POF)?

Peripheral ossifying fibroma (POF) is a non-neoplastic entity, which occurs on the gingiva in response to trauma or irritation. It is a reactive lesion of connective tissue and is not the soft-tissue counterpart of central ossifying fibroma.

What is the histopathology of osteogenesis imperfecta (POF)?

Besides, histopathology of ossifying fibromas occurring in areas such as skull, femur and tibia, where cementum is absent, also show similar histopathology.[5] CONCLUSION POF is a pathological entity whose histogenesis is yet to be delineated. It shares a varied clinic-pathological presentation.

What is the pathophysiology of posterior maxilla osteogenesis imperfecta?

The anterior maxilla is the most common location of involvement. The etiology and pathogenesis of POF remains unknown. Some investigators consider it a neoplastic process, whereas others argue that it is a reactive process; in either case, the lesion is thought to arise from cells in the periodontal ligament.